COLLAGEN Q  & A

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Collagen and Skin

The deepest layers of the skin are built from a dense network of collagen fibers. It’s this collagen-rich layer that provides a firm and resilient foundation for a youthful-looking complexion.

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A special group of skin cells, known as fibroblasts, builds and maintains your skin’s collagen layer. These hard-working skin cells also create elastin, a type of fiber that gives skin its elasticity and resilience, and hyaluronic acid, a substance that helps maintain skin moisture and hydration.

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Skin is exposed to damaging environmental stressors like UV rays from the sun and pollution.  Over time, these environmental exposures fragment collagen fibers and deplete the skin of active fibroblasts (1). Slowed collagen synthesis can’t keep up with accumulated damage to collagen fibers, and the result is thinner, drier skin and wrinkles, among other visible signs of aging (2).

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How Collagen Peptides Benefit Skin

Researchers have studied the impact of collagen peptide supplements on skin health for years. Clinical trials consistently show the benefits of collagen peptides for enhancing skin hydration and elasticity as well as promoting a diminished appearance of fine lines and wrinkles (3). Ongoing research is now investigating how collagen peptides benefit the skin in detail, and research suggests that collagen peptides may support skin health in several ways.

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Collagen peptides help to accelerate the production of new collagen in the skin by providing ready-to-use building materials that support collagen synthesis. In one study, researchers used advanced imaging techniques to measure the density and fragmentation of the collagen layer of the participant’s skin. After consuming a daily collagen peptide supplement for 12 weeks, participants had a significantly greater collagen density, and significantly decreased collagen fragmentation in their skin (4). These impressive changes resulted from greater building and repair of collagen experienced by the participants in this study.

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In addition to promoting collagen synthesis, research suggests that collagen peptides may also support the ability of fibroblasts in the skin to produce elastin, hyaluronic acid, and other factors that benefit skin health (4-6). These effects of collagen peptides may contribute to improved skin elasticity and hydration.

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How Long Does It Take for Collagen Supplements to Work?

The right collagen supplement can deliver visible benefits for healthy skin, but noticeable changes don’t happen overnight.

Collagen peptides are the key skin-supporting ingredient you need to experience benefits like improved skin hydration and elasticity along with a diminished appearance of fine lines and wrinkles. These benefits result from the effect that collagen peptides have on the structure and function of your skin.

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How Long Will It Take to See Results?

In one sense, collagen peptide supplements go to work immediately, although you aren’t likely to see changes in the mirror after your first sip. Your skin needs time for rebuilding and renewal, after all.

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Many of the best studies on the benefits of collagen peptides for skin health were conducted over 12 weeks (3). Researchers measured substantial improvements in skin health, including greater skin hydration and elasticity and a diminished appearance of fine lines and wrinkles at the end of the 12-week study period.

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While the research suggests that on average, significant benefits are measurable after 12 weeks, that doesn’t mean you’ll need to wait for 12 weeks before you start to notice an improvement. Renewal and repair are gradual processes that take time. Skin is one of our most individual and unique features. While research is a great guide to help inform expectations, your experience, like your skin, will be unique to you.

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What Is the Impact of Isa's Collagen Peptides Elixir™on the Skincare Market?

Thousand of testimonies and pictures attest to the fact that people are aging young with Isa's products line. After Isa launched the Collagen Elixir in America, it became a viral phenomenon; because of the phenomenal results obtained, months prior, after the product was launched in Australia.  In America, 72 hours after it was launched, in January 2021, 1 million bottles were sold. 2 million in 2 weeks, 3 million in 3 weeks, and the entire 2 years' stock was sold in 5 weeks, more than 40 million bottles sold in one year. The revenue registered by the company with this product alone is 160 million in one year. A total market disrupter.  

 

Which Form of Collagen is Most Effective?

You have heard the claim that powder collagen is better than liquid one, and others say that the liquid is better. One critical fact, that people ignore is that every time they open a multi-dosage bottle filled with a liquid or powder form of collagen, the product gets in contact with the air, causing it to oxide. This action reduces its potency.  They are cheaper, but the long-term result is negatively affected. To avoid oxidation, the collagen Elixir comes in recyclable individual bottles, and no preservatives were used. Those are two of the many reasons that set the company Isa and the Collagen Elixir apart from all others. ​

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What is the Source of the Fish in the Collagen Peptides Elixir™?

Isa's marine collagen is sourced from wild-caught fish found in the crystal-clear waters in the North Atlantic Ocean, including around Scandinavia. The marine collagen is extracted from the collagen-rich parts of the harvested fish while the rest is fully utilized for other purposes. To maintain maximum freshness, the marine collagen in Collagen Elixir is extracted on location, hydrolyzed with natural enzymes, and dried for maximum stability. The marine collagen is then ready for transport to Isa's world-class LEED green building-certified manufacturer. 

 

Why Can't We Just Eat the Fish to Receive the Collagen We Need?

While the fish we eat contains collagen, it’s in the form of long-collagen fibers, and they are hard for the body to digest and use. But, the Isa Collagen Elixir, combines highly bioavailable collagen peptides along with vitamins and minerals to quickly deliver collagen’s benefits, throughout the body. Studies show that supplementing with marine collagen alone, or when combined with other nutrients such as vitamin C and zinc, it improves skin hydration, elasticity, and thickness. It also improves the aspects of hair and nails and minimizes the appearance of fine lines, wrinkles, and stretch marks. For these reasons, Collagen Peptides Elixir was created with Ingredients found on land and on the sea. It is made with hydrolyzed marine collagen synergistically blended with a powerful botanical blend and micronutrients to help nourish our skin from the inside out. 

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Were Preservatives Used in the Development of the Collagen Elixir? 

Collagen Elixir is scientifically based, manufactured in a carbon-neutral world-leading manufacturing facility, and transported in oxidation-resistant 100% recyclable glass bottles. In order to preserve the efficacity of the collagen peptides, each bottle is sealed in just 0.15 seconds to prevent gas exchange and oxidation. This helps to maintain a premium quality and avoid the use of artificial preservatives. Also, Collagen Peptides Elixir is packaged in single-bottle per dose to avoid oxidation. When consumers buy collagen, in liquid or powder form, that is sold in a big bottle or a jar, every time they open it to consume, the collagen gets in contact with oxygen, which causes it to oxidize, therefore, it gradually loses its efficacy. 

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Was Collagen Elixir Made with Sustainably Sourced Ingredients 

Collagen Elixir is made with sustainably sourced ingredients and arrives in 100% recyclable packaging. Isa's sustainability philosophy is simple: Celebrate Growth and Achievement while Protecting the Planet.  Once you’ve enjoyed your Collagen Elixir, don’t forget to recycle your cardboard boxes and glass bottles to continue promoting sustainability in its life cycle.

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Isa uses wild fish from the North Atlantic Ocean and the Scandinavian waters where local fishermen harvest wild-caught fish following strict fishing industry practices known for protecting the ocean and sustainable fishing stocks. Isa partners only with suppliers who are also certified by the Marine Stewardship Council (the global standard for sustainable fishing). This way, they help promote marine biodiversity by eliminating overfishing and minimizing impacts on the environment.

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How Does Isa Assure the Purity of the Hydrolyzed Collagen Peptides?

The hydrolyzed collagen peptides in Collagen Elixir are derived from Scandinavian, cold–water cod, pollock, and haddock that are generally lower in mercury compared to top-of-the-food-chain fish like tuna and swordfish. Once the collagen has been purified to hydrolyzed collagen peptides, the raw material is tested for mercury and heavy metals to ensure purity, quality, and safety. In addition to the raw material testing, Isagenix sends every finished batch of Collagen Elixir for third-party independent testing, which includes mercury and heavy metals.

Isagenix follows a strict no-compromise commitment and prioritizes the purity, safety, and efficacy of all products.

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References

1. Fisher GJ, Varani J, Voorhees JJ. Looking older: fibroblast collapse and therapeutic implications. Arch Dermatol. 2008;144(5):666-672. doi:10.1001/archderm.144.5.666

2. Fisher GJ, Kang S, Varani J, et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol. 2002;138(11):1462-1470. doi:10.1001/archderm.138.11.1462

3. de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021;60(12):1449-1461. doi:10.1111/ijd.15518

4. Asserin J, Lati E, Shioya T, Prawitt J. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015;14(4):291-301. doi:10.1111/jocd.12174

5. Ohara H, Ichikawa S, Matsumoto H, et al. Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. J Dermatol. 2010;37(4):330-338.

6. Edgar S, Hopley B, Genovese L, Sibilla S, Laight D, Shute J. Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts. Sci Rep. 2018;8(1):10474. Published 2018 Jul 11. doi:10.1038/s41598-018-28492-w

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